Buongiorno,
WOW - that is a tall order, there are so many places you could base yourself depending on what you really want to explore while in Tuscany.
Here are just a few of the place you could look at, these are places I have personally visited so, the article gives you a bit of info on what there is to see and explore:
https://www.discovertuscany.com/san-...borghetto.html
(elegant and relaxing)
https://www.discovertuscany.com/tusc...-casanova.html
(they are kid friendly - but very suitable for a couple traveling in Tuscany)
https://www.visitflorence.com/bed-an...e-le-cave.html
(I know it is a B&B but they have apartments with kitchens)
https://www.discovertuscany.com/tusc...a-moriano.html
(on a wine producing estate)
Buon Viaggio,
Donna Denise
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